Ameliorate Effect of Ajwa (Phoenix dactylifera) on C-Reactive Protein, Lipid Profile and Cardiac Histopathology in Rabbits

Authors

  • Aisha Saleem M.Phil Researcher School of Zoology, Minhaj University Lahore
  • Irum Naureen Assistant professor, School of Zoology Minhaj University Lahore
  • Aadab Akhtar GC Women university Sialkot
  • Gulnaz Tasleem M.Phil Researcher School of Zoology, Minhaj University Lahore
  • Sara Chaudhry M.Phil Researcher School of Zoology, Minhaj University Lahore
  • Attique Nawaz M.Phil Researcher School of Zoology, Minhaj University Lahore
  • Sabeen Ijaz Centre of Applied molecular Biology and Forensic sciences
  • Muhammad Naeem Institute of Research and Information Mirpur AJK, Pakistan
  • Zaib ul Nisa M.Phil Researcher School of Zoology, Minhaj University Lahore

Keywords:

Cardiovascular diseases, Lipid profile, hs-CRP, CRP, ELISA

Abstract

Background: High fat diet causes oxidation of accumulated fat cells which leads to Atherosclerosis. The inflammatory marker C-reactive protein has recently been identified as an independent predictor of future coronary heart disease. The inflammatory marker C-reactive protein has recently been identified as an independent predictor of future coronary heart disease. Present study evaluated the cardioprotective role of Ajwa seed paste on lipid profile and C-reactive protein (CRP) level in rabbits. Methodology: 7 months old rabbits (n=15) for 30 days were kept in animal house school under standard laboratory conditions. Rabbits were divided into three groups (n=5). Group1 served as control group fed basal diet, group 2 fed high fat diet, group 3 fed high fat diet supplemented with 6gm ajwa seed paste. Feed consumption ratio was determined in all groups on daily basis.  Results: Feed consumption ratio showed significant (P>0.05) decrease in group 2and 3 fed high fat diet. In this study, lipid profile (cholesterol, triglyceride, LDL and VLDL) values were increased in group 2 compared to control group. It was found that significant (P>0.05) decrease in the level of bad cholesterol (LDL, VLDL) in group 3 (fed ajwa seed supplemented diet).HDL value showed significant (P>0.05) increase in group 3. HDL is good cholesterol and increased the level of HDL protect against the stroke and heart attack. and increase the level of good cholesterol (HDL).HDL takes the cholesterol from the body and back to liver where liver removes the bad cholesterol. The value of CRP is higher in group 2 due to the consumption of HFD and CRP level in group 3 showed significant (P>0.05) reduction.  Conclusion: It is concluded from present study that ajwa seed paste is beneficial for heart health.

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Published

2024-07-09

How to Cite

Aisha Saleem, Irum Naureen, Aadab Akhtar, Gulnaz Tasleem, Sara Chaudhry, Attique Nawaz, Sabeen Ijaz, Muhammad Naeem, & Zaib ul Nisa. (2024). Ameliorate Effect of Ajwa (Phoenix dactylifera) on C-Reactive Protein, Lipid Profile and Cardiac Histopathology in Rabbits. American Scientific Research Journal for Engineering, Technology, and Sciences, 98(1), 144–157. Retrieved from https://www.asrjetsjournal.org/index.php/American_Scientific_Journal/article/view/10583

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