Comparison of Antioxidant and Anti-hyaluronidase Activity of Tomato (Solanum lycopersicum L.) Extract and Lycopene

  • Djohan Djohan Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • Kristina Kristina Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • Alhoi Hendry Henderson Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • I Nyoman Ehrich Lister Department of Physiology, Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • Ermi Girsang Faculty of Public Health, Universitas Prima Indonesia, Medan, Indonesia
  • Edy Fachrial Laboratory of Biomolecular, Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
Keywords: Antioxidant, Hyaluronidase, Solanum lycopersicum L., Lycopene, Antiaging.

Abstract

Aging process contributed with poor of lifestyle and photodamage can induced wrinkles formation because of extracellular matrix destruction. To investigate the potential of tomato as antiaging sources particularly as the hyaluronidase inhibitor. This study used H2O2 scavenging activity for antioxidant assay and hyaluronidase inhibition activity for the antiaging property.  The Solanum lycopersicum L. extract (SLE) has lower antioxidant activity (221.30 ± 1.94) compared with lycopene (208.37 ± 4.87) through H2O2 scavenging activity. The Solanum lycopersicum L. (119.81 ± 14.23) has lower antiaging activity particularly as anti-hyaluronidase activity compared with lycopene (81.65 ± 5.95). Our findings suggest that the Solanum lycopersicum L. has weak antioxidant activity and moderate antiaging activity, particularly as a hyaluronidase inhibitor. Solanum lycopersicum L. can be used as an antiaging source, particularly as hyaluronidase inhibitor.

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Published
2019-01-30
Issue
Vol 52 No 1 (2019)
Section
Articles

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