A Comparative Study of Peel and Seed Extract of Passion Fruit (Passiflora edulis) as Antihyaluronidase
AbstractThe plant produces various metabolites and one among the benefit is to inhibit the aging process. The aim of the study was to compare the antioxidant activity between the peel and the seeds of P.edulis and also to compare anti-hyaluronidase activity. The antioxidant activity was determined using the ABTS reduction method. The result showed that the reduction percentage of ABTS of seed and peel of P.edulis was 15,58 ± 1,04 % and 27,68± 0,09 % respectively at concentration 50 µg/ml. The inhibition activity of hyaluronidase of seed and peel of P.edulis was 70,96 ± 3,55 % and 61,68 ±4,05 %. The IC50 of anti hyaluronidase activity of seed dan peel extract was 122,70 ± 6,35 and 67,35 ±6,58 respectively. From the result, it can be concluded that the seeds and peel of P.edulis have the potential as a source of anti-aging particularly as anti hyaluronidase.
G. Ndlovu, G. Fouche, M. Tselanyane, W. Cordier, and V. Steenkamp, “In vitro determination of the anti-aging potential of four southern African medicinal plants,” BMC Complement. Altern. Med., vol. 13, 2013.
N. Khare, P. Khare, and G. Yadav, “Recent Advances in Anti-Aging – A Review,” Glob. J. Pharmacol., vol. 9, no. 3, pp. 267–271, 2015.
L. Baumann, “Skin aging and its treatment,” J. Pathol., vol. 211, no. 2, pp. 241–251, 2007.
E. Papakonstantinou, M. Roth, and G. Karakiulakis, “Hyaluronic acid: A key molecule in skin aging,” Dermatoendocrinol., vol. 4, no. 3, 2012.
R. Ganceviciene, A. I. Liakou, A. Theodoridis, E. Makrantonaki, and C. C. Zouboulis, “Skin anti-aging strategies.,” Dermatoendocrinol., vol. 4, no. 3, pp. 308–19, 2012.
G. D. Liyanaarachchi, J. K. R. R. Samarasekera, K. R. R. Mahanama, and K. D. P. Hemalal, “Tyrosinase, elastase, hyaluronidase, the inhibitory and antioxidant activity of Sri Lankan medicinal plants for novel cosmeceuticals,” Ind. Crops Prod., vol. 111, no. January, pp. 597–605, 2018.
S. S. Patel, “Morphology and pharmacology of Passiflora edulis: A review,” J. Herb. Med. Toxicol., vol. 3, no. 1, pp. 1–6, 2009.
W. Widowati et al., “Antioxidant and Anti Aging Assays of <I>Oryza sativa</I> Extracts, Vanillin and Coumaric Acid,” J. Nat. Remedies, vol. 16, no. 3, p. 88, 2016.
H. H. Orak, H. Yagar, and S. S. Isbilir, “Comparison of antioxidant activities of juice, peel, and seed of pomegranate (Punica granatum L.) and inter-relationships with total phenolic, Tannin, anthocyanin, and flavonoid contents,” Food Sci. Biotechnol., vol. 21, no. 2, pp. 373–387, 2012.
Y. K. Ang, W. C. M. Sia, H. E. Khoo, and H. S. Yim, “Antioxidant potential of Carica papaya peel and seed,” Focus. Mod. Food Ind., vol. 1, no. 1, pp. 11–16, 2012.
J. R. Sihombing, A. Dharma, Z. Chaidir, E. Fachrial, and E. Munaf, “Journal of Chemical and Pharmaceutical Research , 2015 , 7 ( 11 ): 190-196 Research Article Phytochemical screening and antioxidant activities of 31 fruit peel extract from Sumatera , Indonesia,” vol. 7, no. 11, pp. 190–196, 2015.
I. Fidrianny, A. Rizkiya, and K. Ruslan, “Antioxidant activities of various fruit extracts from three solanum sp. using DPPH and ABTS method and correlation with phenolic, flavonoid and carotenoid content,” J. Chem. Pharm. Res., vol. 7, no. 5, pp. 666–672, 2015.
P. T. B. Tu and S. Tawata, “Anti-oxidant, anti-aging, and anti-melanogenic properties of the essential oils from two varieties of Alpinia zerumbet,” Molecules, vol. 20, no. 9, pp. 16723–16740, 2015.
A. Sahasrabudhe and M. Deodhar, “Anti-hyaluronidase, anti-elastase activity of Garcinia indica,” International Journal of Botany, vol. 6, no. 3. pp. 299–303, 2010.
T. Shibata, K. Fujimoto, K. Nagayama, K. Yamaguchi, and T. Nakamura, “Inhibitory activity of brown algal phlorotannins against hyaluronidase,” Int. J. Food Sci. Technol., vol. 37, no. 6, pp. 703–709, 2002.
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