Antioxidant and Anticollagenase Activity of Tomato (Solanum lycopersicum L.) and Lycopene
Keywords:
Solanum lycopersicum L., Antiaging, Collagenase, Antioxidant.Abstract
Antioxidants were any substance that can inhibit oxidation that causes collagen disintegration, lipid breakdown, DNA damage and protein unfolding in the aging process. The ingredients in the cosmetics has a toxin effect in human body. To investigate the bioactive compound, an antioxidant and antiaging activity particularly as collagenase inhibitor of the tomatoes. This study used phytochemical screening for the bioactive compounds, DPPH scavenging activity for antioxidant assay and collagenase inhibition activity for the antiaging property. The phytochemical screening shows that the Solanum lycopersicum L. extract (SLE) has flavonoid, phenol, saponin, tannin and alkaloid. The lycopene (79.45 ± 1.01) has an antioxidant activity better than SLE (147.20 ± 16.97) from DPPH scavenging activity. Lycopene (85,09 ± 1,81 ?g/mL) also has the higher antiaging activity than SLE (236,74 ± 9,74 ?g/mL) particularly as collagenase inhibitor. In conclusion flavonoid was the most common in the SLE. SLE has a higher antioxidant activity through DPPH scavenging activity and antiaging activity particularly as a collagenase inhibitor.
References
KS. Sonam, S. Guleria. “Synergistic Antioxidant Activity of Natural Products”. Annals of Pharmacology and Pharmaceutics, vol. 2(16), pp. 1-6. Sep. 2017.
EA. Sisein. “Biochemistry of Free Radicals and Antioxidants”. Scholars Academic Journal of Biosciences, vol. 2(2), pp. 110-8. 2014.
OE. Ifeanyi. “A Review on Free Radicals and Antioxidants”. International Journal of Current Research in Medical Sciences, vol. 4(2), pp. 123-33. 2016.
W. Widowati, AP. Rani, RA.Hamzah, S. Arumwardana, E. Afifah, HSW. Kusuma, DD. Rihibiha, H. Nufus, A. Amalia. “Antioxidant and Antiaging Assays of Hibiscus sabdariffa Extract and Its Compounds”. Natural Product Sciences, vol. 23(3), pp. 192-200. 2017.
Manisha, W. Hasan, R. Rajak, D. Jat. “Oxidative Stress and Antioxidants: An Overview”. International Journal of Advanced Research and Review. Vol. 2(9), pp. 110-9. 2017.
DB. Kapadiya, BK. Dabhi, KD. Aparnathi. “Spices and Herbs as a Source of Natural Antioxidants for Food”. International Journal of Current Microbiology and Applied Sciences, vol. 5(7), pp. 280-8. Jul. 2016.
V. Jadhav, S. Dhande, V. Kadam. “Cosmetic Side Effects”. World Journal of Pharmacy and Pharmaceutical Sciences, vol. 6(1), pp. 327-343. Dec. 2016.
W. Klunklin, G. Savage. “Effect on Quality Characteristics of Tomatoes Grown Under Well-Watered and Drought Stress Conditions”. Foods, vol. 6(56), pp. 1-10. Jul. 2017.
V. Nour, I. Trandafir, ME. Ionica. “Antioxidant Compounds, Mineral Content And Antioxidant Activity Of Several Tomato Cultivars Grown In Southwestern Romania”. Not Bot Horti Agrobo, vol. 41(1), pp. 136-142. 2013.
SC. Mondal, P. Singh, B. Kumar, SK. Singh, SK. Gupta, A. Verma. Ageing and Potential Anti-Aging Phytochemicals: An Overview. World Journal of Pharmacy and Pharmaceutical Sciences, vol. 4(1), pp. 426-54. Dec. 2015.
MA. Shahtalebi, AH. Siadat, S. Karbasizade. “Preparation and Evaluation of the Clinical Efficacy and Safety of Tomato Lotion Containing Lycopene”. Journal of HerbMed Pharmacology, vol. 4(4), pp. 142-8. Jul. 2015.
JR. Sihombing, A. Dharma, Z. Chaidir, Almahdy, E. Fachrial, E. Munaf. “Phytochemical Screening and Antioxidant Activities of 31 Fruit Peel Extract from Sumatera, Indonesia”. Journal of Chemical and Pharmaceutical Research, vol. 7(11), pp. 190-6. 2015.
D. Rusmana, R. Wahyudianingsih, M. Elisabeth, Balqis, Maesaroh, W. Widowati. “Antioxidant Activity of Phyllanthus niruri Extract, Rutin and Quercetin”. The Indonesia Biomedical Journal, vol. 9(2), pp. 84-90. May. 2017.
M. Umar, A. Zubairu, HS. Hamisu, IB. Mohammed, JO. Oko, IM. Abdulkarim, A. Salisu, AA. Yaya, AA. Aliko. “Evaluation of Phyotochemical and In Vitro Antiomcrobial Effects of Solanum lycopersicum Linn. (Tomato) on Oral Thrush and Human Cariogenic Pathogens. Journal of Advances in Medical and Pharmaceutical, vol. 11(4), pp. 1-9. Jan. 2016.
W. Widowati, T. Herlina, H. Ratnawati, G. Constantia, IDGS. Deva, M. Maesaroh. “Antioxidant Potential Of Black, Green And Oolong Tea Menthanol Extracts”. Biology, Medicine, & Natural Product Chemistry, vol. 4(2), pp. 38-43. 2015.
W. Widowati, N. Fauziah, H. Herdiman, M. Afni, E. Afifah, HSW. Kusuma, H. Nufus, S. Arumwardana, DD. Rihibiha. “Antioxidant and Anti Aging Assays of Oryza Sativa Extracts, Vanillin and Coumaric Acid”. Journal of Natural Remedies, vol. 16(3), pp. 88-99. Jul. 2016.
R. Karamian, M. Asadbegy. “Antioxidant Activity, Total Phenolic and Flavonoid Contents of Three Onobrychis Species From Iran”. Pharmaceutical sciences, vol. 22, pp. 112-9. Jun. 2016.
W. Widowati, WB. Janeva, S. Nadya, A. Amalia, S. Arumwardana, HSW. Kusuma, Y. Arinta. “Antioxidant and Antiaging Activities of Jasminum Sambac Extract, and Its Compounds”. Journal of Repots in Pharmaceutical Sciences, vol. 7(3), pp. 270-85. Jul. 2018.
RK. Sahu, M. Kar, R. Routray. “DPPH Free Radical Scavenging Activity of Some Leafy Vegetables Used by Tribals of Odisha, India”. Journal of Pharmacognosy and Phytochemistry, vol. 4(1), pp. 21-7. 2013.
B. Boulanouar, G. Hadjira, R. Maria, G. Abdelaziz. DPPH Free Radical Scavenging Activity of Ethanolic Extract of Twenty Two Medicinal Species from South Algeria (Laghouat Region)”. Medicinal & Analytical Chemistry International Journal, vol. 1(1):1-7. Aug. 2017.
I. Firdrianny, A. Rizkiya, K. Ruslan. “Antioxidant Activities of Various Fruit Extracts from Three Solanum sp. Using DPPH and ABTS Method and Correlation with Phenolic, Flavonoid and Carotenoid Content”. Journal of Chemical and Pharmaceutical Research, vol. 7(5), pp. 666-72. 2015.
ASN. Formagio, CRF. Volobuff, M. Santiago, CAL. Cardoso, MDC. Vieira, ZV. Pereira. “Evaluation of Antioxidant Activity, Total Flavonoids, Tannins and Phenolic Compounds in Psychotria Leaf Extracts”. Antioxidants,vol. 3, pp. 745-57. Nov. 2014.
OA. Ojo, CO. Akintayo. “Assessment of Antioxidant Activity of Ficus Asperifolia Miq Aqueous Extract In Vitro Studies”. The Journal of Phytopharmacology, vol. 3(1), pp. 16-21. Feb. 2014.
S. Basumatary, AK. Das, R. Nanjian, GD. Sharma. “In Vitro Evaluation of Antioxidant Properties of Hodgsonia Heteroclita (Cucurbitaceae) Fruit”. Journal of Applied Pharmaceutical Science, vol. 5(3), pp. 80-3. Nov. 2015.
MIA. Rodrigue, LGR. Barros, ML. Sanchez. “Collagen: A Review on Its Sources and Potential Cosmetic Applications”. Journalof Cosmetic Dermatology, vol. 17, pp. 20-6. 2018.
S. Utami, P. Adityaningsari, I. Sosiawan, S. Endrini, QR. Sachrowardi, SP. Laksono, S. Nafik, BC. Arrahmani, et al. “Antioxidants and Anticholinesterase Activities of the Characterized Ethanolic of ripe Sesoot (Garcinia picrorrhiza Miq.) Fruit Extract (GpKar) and Xanthone”. Traditional Medicine Journal, vol. 22(3), pp. 160-5. Dec. 2017.
P. Limtrakul, S. Yodkeeree, P. Thippraphan, W. Punfa, J. Srisomboon. “Anti-aging and Tyrosinase Inhibition Effects of Cassia fistula Flower Butanolic Extract”. BMC Complementary and Alternative Medicine, vol. 16(497), pp. 1-9. 2016.
G. Ndlovu, G. Fouche, M. Tselanyane, W. Cordier, V. Steenkamp. “In Vitro Determination of the Anti-Aging Potential of Four Southern African Medicinal Plants”. BMC Complementary and Alternative Medicine, vol. 13, pp. 1-7. Dec. 2013.
A. Simo, N. Kawal, G. Paliyath, M. Bakovic. “Botanical Antioxidants for Skin Health in the World of Cosmeceuticals”. International Journal of Advanced Nutrituonal and Health Science, vol. 2(1), pp. 67-88. Aug. 2014.
Downloads
Published
How to Cite
Issue
Section
License
Authors who submit papers with this journal agree to the following terms.