Potential ABTS Reducing and Anti-collagenase Activity of Scutellarein and Apigenin

  • Felicia Felicia Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • Ermi Girsang Department of Public Health, Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • Ali Napiah Nasution Department of Tropical Medicine, Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
  • I Nyoman Ehrich Liester Department of Physiology, Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia
Keywords: Scutellarein, apigenin, ABTS, anti-collagenase, Antioxidant, antiaging.

Abstract

In developed and developing countries, the aging population growth rapidly and the consumption of natural product which rich antioxidant increasing. The aim of this study was to investigate the ABTS reducing activity and anti-collagenase activity of scutellarein and apigenin. This study used ABTS reducing activity for antioxidant assay and collagenase inhibitory activity for antiaging assay. Scutellarein (16.77 μg/ml) has higher antioxidant activity through ABTS reducing activity compared with apigenin (80.19 μg/ml). Scutellarein (99.20 μg/ml) has higher antiaging activity through collagenase inhibitory activity compared with apigenin (211.67 μg/ml). Scutellarein has very strong antioxidant activity through ABTS reduction activity and strong antiaging property particularly as collagenase inhibitor. Apigenin has strong antioxidant activity through ABTS reduction activity and weak antiaging property particularly as collagenase inhibitor.

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Published
2019-07-19
Issue
Vol 57 No 1 (2019)
Section
Articles

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